Three dimensional visualization of histopathological data

Abstract

The histopathological examination provides information about the spatial assessment of pathological changes in the tissue. The authors present a method of extending this histopathological spatial assessment with a 3D view consisting of images of microscopic layers. The proposed solution creates 3D models based on images obtained from the database of the Medical University of Gdańsk (Digital Pathology). First, a series of medical images related to the study of a specific pathological tissue undergoes a process of background detection and removal through an algorithm. Next, images aligned with each other. Then, two types of 3D models are created: 1) classical model with Marching Cubes algorithm and 2) the use Cloud of Points.