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TASK Quarterly

STRUCTURAL SIMILARITY OF CheY-LIKE PROTEINS

Abstract

The problem of structural similarity of polypeptide chains of low sequence similarity representing a similar 3D structural form has been the object of analysis of researchers engaged in the protein folding problem. Three homologous proteins of similar biological function with low sequence similarity are the objects of analysis presented in this paper. The structure of a hydrophobic core is used as the criterion for structural similarity assessment of these three proteins. The applied method allows recognition of differentiation in topologically similar structures.

Keywords:

hydrophobicity, tertiary structure, hydrophobic core

Details

Issue
Vol. 20 No. 4 (2016)
Section
Research article
Published
2016-12-29
DOI:
https://doi.org/10.17466/tq2016/20.4/j
Licencja:
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biography

IRENA ROTERMAN,
Jagiellonian University – Medical College, Department of Bioinformatics and Telemedicine



Authors

  • MATEUSZ BANACH

    Jagiellonian University – Medical College, Department of Bioinformatics and Telemedicine
  • LESZEK KONIECZNY

    Jagiellonian University – Medical College, Chair of Medical Biochemistry
  • IRENA ROTERMAN

    Jagiellonian University – Medical College, Department of Bioinformatics and Telemedicine

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